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Treatment of Perianal Disease Using Adipose-derived Stem Cells

Phase Not Applicable


Doctors at the University of California San Diego are recruiting patients with perianal fistula, including those caused by Crohn’s Disease, to receive an experimental treatment that transfers adipose (fat tissue)-derived stem cells to the fistula lesion.

This investigatory treatment aims to assure the effectiveness of the treatment in comparison with standard surgical care.


  • Be 18 years of age and older
  • Diagnosis of perianal disease with tissue defect or chronic wound
  • Not be pregnant


  1. Prescreening at the study site to confirm eligibility of the patient to participate.
  2. Stem cells will be drawn from the patient’s adipose, or fat, tissue, by liposuction method.
  3. During the same surgery, a colorectal surgeon will perform an exam and determine if any additional procedure such as ligation of fistula tract, fistulotomy, endorectal advancement flap, or seton placement/exchange is needed.
  4. Then the surgeon will inject the adipose stem cells, after they are processed by the Acelity machine, into the perianal fistula.


Trials will take place at the University of California San Diego. Map.

Contact: Samuel Eisenstein, MD  |  203-560-2213  |  [email protected]

Contact: Sarah Stringfield, MD  |  920-319-1697  |  [email protected]



University of California, San Diego


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