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Clinical Trials Archives - Healing Genes
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Diffuse Intrinsic Pontine Glioma

Phase I Study of Autologous T Lymphocytes Expressing GD2-specific Chimeric Antigen and Constitutively Active IL-7 Receptors for the Treatment of Patients With GD2-expressing Brain Tumors (GAIL-B) C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) Phase 1 DESCRIPTION: Researchers in Texas Children's Hospital are seeking for patients with high grade glioma (HGG)...

Peripheral Artery Disease

Hepatocyte Growth Factor to Improve Functioning in PAD (HI-PAD) Hepatocyte Growth Factor to Improve Functioning in Peripheral Artery Disease: The HI-PAD Study Phase 3 DESCRIPTION: Northwestern University researchers are seeking 39 people with peripheral artery disease (PAD) who do not have critical limb ischemia for an investigatory therapy. The...

Ovarian Cancer

A Study of VB-111 With Paclitaxel vs Paclitaxel for Treatment of Recurrent Platinum-Resistant Ovarian Cancer (OVAL) (OVAL) A Randomized, Controlled, Double-Arm, Double-Blind, Multi-Center Study of Ofranergene Obadenovec (VB-111) Combined With Paclitaxel vs. Paclitaxel Combined With Placebo for the Treatment of Recurrent Platinum-Resistant Ovarian Cancer Phase 3 DESCRIPTION: Doctors at...

High Grade Glioma (HGG)

A Study of the Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subjects With Newly Diagnosed High Grade Glioma Receiving Standard of Care (Toca7) The Toca 7 Study: A Phase 1b Study of the Safety of Toca 511, a Retroviral Replicating...

Multicenter RCT of ADV-TK Gene Therapy Improving the Outcome of Liver Transplantation for Advanced HCC

Multicenter RCT of ADV-TK Gene Therapy Improving the Outcome of Liver Transplantation for Advanced HCC Multicenter Randomized Controlled Trial of Adenovirus-mediated Adjuvant Gene Therapy Improving Outcome of Liver Transplantation in Patients With Advanced Hepatocellular Carcinoma Phase 3 DESCRIPTION: Researchers in China are seeking patients with advanced hepatocellular carcinoma, who...

Recurrent Prostate Cancer

Phase 3 Study of ProstAtak® Immunotherapy With Standard Radiation Therapy for Localized Prostate Cancer (PrTK03) A Randomized Controlled Trial of ProstAtak® as Adjuvant to Up-front Radiation Therapy For Localized Prostate Cancer Phase 3 DESCRIPTION: Researchers at 57 US study centers are recruiting over 700 participants to trial a prostate...

Corneal Epithelial Defects

NEXAGON for the Treatment of Corneal Persistent Epithelial Defects Following Severe Ocular Chemical and/or Thermal Injuries (EXPEDE) A Phase 2, Randomized, Prospective, Double-masked, Vehicle-controlled Study to Assess the Efficacy and Safety of Nexagon® (NEXAGON) Applied Topically in Subjects With Corneal Persistent Epithelial Defects Resulting From Severe...

Transfusion-Dependent β-Thalassemia

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Subjects With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype A Phase 3 Single Arm Study Evaluating the Efficacy and Safety of Gene Therapy in Subjects With Transfusion-dependent β-Thalassemia, Who do...

Metachromatic Leukodystrophy (MLD)

A Safety and Efficacy Study of Cryopreserved OTL-200 for Treatment of Metachromatic Leukodystrophy (MLD) A Single Arm, Open Label, Clinical Study of Cryopreserved Autologous CD34+ Cells Transduced With Lentiviral Vector Containing Human ARSA cDNA (OTL-200), for the Treatment of Early Onset Metachromatic Leukodystrophy (MLD) Phase 2 DESCRIPTION: Doctors at...

Myocardial Ischemia

Ad5FGF-4 In Patients With Refractory Angina Due to Myocardial Ischemia (AFFIRM) A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter, Phase 3 Study to Evaluate the Safety and Efficacy of Ad5FGF-4 in Patients With Refractory Angina Due to Myocardial Ischemia Phase 3 DESCRIPTION: Researchers at Angiogetics Inc. seek participants for clinical...